Fundação Oswaldo Cruz - FioCruz (Curitiba, Brazil)

Assay development for Chagas disease
The Oswaldo Cruz Foundation (Portuguese Fundação Oswaldo Cruz, also known as FioCruz) is a scientific institution for research and development in biomedical sciences located in Rio de Janeiro, Brazil, it is considered one of the world's main public health research institution.

It was founded by Dr. Oswaldo Cruz, a noted physician and epidemiologist.
To promote health and social development, to forge and disseminate scientific and technological knowledge, to be an agent of citizenship. These are the concepts that have guided Fundação Oswaldo Cruz (Oswaldo Cruz Foundation, known as Fiocruz), attached to the Brazilian Ministry of Health and the most prominent science and technology health institution in Latin America.
Inaugurated on May 25, 1900 under the name of Federal Serotherapy Institute, Fiocruz was given the mission of fighting the great problems of public health in Brazil. Therefore, Fiocruz became a think tank concerned with the Brazilian reality and experimental medicine.
Today the institution is responsible for a range of activities which include research development; highly-regarded hospital and ambulatory care services; production of vaccines, drugs, reagents, and diagnostic kits; education and training of human resources; information and communication in the area of health, science and technology; quality control of products and services, and the implementation of social programs. It has over 10,500 employees and health professionals with different levels of involvement, a workforce proud of being at the service of life. Fiocruz contributes to improving health throughout the country, through its support to the Sistema Único de Saúde (Unified Health System, the Brazilian public health system), its proposals on public health policy-making, its research activities, its scientific expeditions, and the reach of its health services and products.
Fiocruz is based at a 800,000-square meter campus in Manguinhos, a neighbourhood in the northern part of the city of Rio de Janeiro. Around the three historical buildings of the old Federal Serotherapy Institute – the Moorish Pavilion, the Clock Pavilion and the Mews -, are located ten of Fiocruz’s thirteen technical-scientific units and all the technical and administrative support units. Another five units are located in Rio de Janeiro, Belo Horizonte, Salvador, Recife and Manaus.


IBMP, Instituto de Biologia Molecular de Paraná, is an institution that was founded by Fiocruz and the Secretaria of Science and Technology in the year 2001, to promote the development of research and projects in the area of human and animal health. Especially to focus on the so called neglected diseases. IBMP is one of the centers of excellence in terms of research and science in the field of applied molecular biology. IBMP is located on the campus of TECPAR in Curitiba the capital of the state Paraná closely to the Instituto Charlos Chagas from Fiocruz.
IBMP has the capability for the production of diagnostics kit reagents in its 2000 m² state of the art cGMP production facilities as well as 250 m² development area. Actually 25 People are employed at IBMP.
The main research and technological development areas are:

  • Molecular basis of the differentiation of Trypanosma cruzi
  • Enzym determination for the chemotherapy of Chagas and Dengue disease
  • Development of recombinant antigens for diagnostic purposes
  • Functional genome studies
  • Bioinformatics on the analysis of DNA micro arrays
  • Development on the improvement of vaccines

The main mission of IBMP is to reinforce the competence of Paraná in the field of biotechnology, to introduce new innovative tools for the public health system and to develop diagnostic kits for the detection of hanta virus, dengue and chagas disease.